TRANSLATIONAL PHYSIOLOGY Gene expression and muscle fiber function in a porcine ICU model
نویسندگان
چکیده
Varuna C. Banduseela, Julien Ochala, Yi-Wen Chen, Hanna Göransson, Holly Norman, Peter Radell, Lars I. Eriksson, Eric P. Hoffman, and Lars Larsson Department of Clinical Neurophysiology, Uppsala University Hospital, Uppsala, Sweden; Research Center for Genetic Medicine, Children National Medical Center; Department of Pediatrics, The George Washington University Medical Center, Washington, District of Columbia; Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden; Department of Physiology, University of Wisconsin, Madison, Wisconsin; and Department of Anesthesiology, Karolinska Institute, Stockholm, Sweden; Department of Biobehavioral Health, Pennsylvania State University, University Park, Pennsylvania
منابع مشابه
Gene expression and muscle fiber function in a porcine ICU model.
Skeletal muscle wasting and impaired muscle function in response to mechanical ventilation and immobilization in intensive care unit (ICU) patients are clinically challenging partly due to 1) the poorly understood intricate cellular and molecular networks and 2) the unavailability of an animal model mimicking this condition. By employing a unique porcine model mimicking the conditions in the IC...
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